Application

Research CategorySignaling

Research Sub CategoryDevelopmental Signaling

Detect LIM Domain Only 2 using this Anti-LIM Domain Only 2 Antibody, clone 2E6 validated for use in WB.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

LIM Domain only 2 (LMO2) encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur.

Immunogen

Recombinant human LMO2

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Physical form

Liquid containing 0.1% sodium azide.

Quality

Routinely evaluated by immunoblot.

Specificity

Human

Storage and Stability

1 year at 4°C from date of shipment

Target description

18kDa